2020.09.17 – TBI and Inflammation Across the Adult Lifespan (Recorded Webinar)

Aired live on September 17, 2020. Includes 1 ACBIS CEU.

Note: A certificate of attendance/ACBIS CEU certificate will not be available with the purchase of this webinar after September 30, 2023.

In this webinar Mitchell Rosenthal Memorial Research webinar speakers present information on TBI and inflammation across the adult lifespan. Information about each presenter and their topic can be found be below.

Does Acute Soccer Heading Cause Neuroinflammation? A Pilot Randomized Clinical Trial

Presenter: Keisuke Kawata, Ph.D., ATC

Repetitive subconcussive head impacts have gained attention due to their potential link to later-onset of neurodegenerative conditions. A series of subconcussion studies using a controlled soccer heading model emerged to support subtle, but detectable levels of neurologic burden from acute soccer headings. This talk will highlight some of the key findings from a recent pilot clinical trial that relate to changes in neuroinflammatory biomarkers and other neurologic cellular factors after acute soccer headings.

Neuroinflammatory Biomarkers Associated with Mild Traumatic Brain Injury History in Special Operations Forces Combat Soldiers

Presenter: Jacob R. Powell, M.S., LAT, ATC

This presentation will describe elevations in neuroinflammatory biomarkers including S100B, neurofilament light, neuron-specific enolase, and IL-6 in special operations combat soldiers associated with mTBI history and recency. Potential mechanisms leading to neuroinflammatory cascades following brain injury and clinical relevance to the special operations forces community will be discussed.

Age-Related Differences in Inflammatory Signatures Following Mild TBI in Adults

Presenter: Hilaire Thompson, Ph.D., RN, ARNP

This presentation will describe findings from a prospective longitudinal cohort study of younger and older adults with and without mild traumatic brain injury. Multiplex assays were used to quantify concentrations of selected plasma inflammatory markers from <24 hours after injury to 6 months post-injury.

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About the Presenters

	Keisuke Kawata is a clinical neuroscientist and athletic trainer. He is an assistant professor in the Department of Kinesiology and Program in Neuroscience. In his laboratory at Indiana University, his team is currently conducting a wide array of subconcussion research in both field and laboratory settings in sports and military cohorts, aiming to understand the short- and long-term effects of subconcussive brain damage and establish a clinical guideline to prevent chronic brain deficits in athletes and military service members.
	Jake R. Powell is a doctoral student in the Interdisciplinary Program in Human Movement Science at the University of North Carolina at Chapel Hill working out of the Matthew Gfeller Sport-Related TBI Research Center. Jacob's research interests include post-mTBI neurobiology and the relationship between clinical presentation of brain injury and physiological recovery.
	Hilaire Thompson, Ph.D., RN, ARNP, FAAN is the Joanne Montgomery Endowed Professor and co-Director of the Omics and Symptom Science Training program at the University of Washington School of Nursing. She is also core faculty and co-director of the Education and Training core of Harborview Injury Prevention and Research Center. Her research is focused on geriatric traumatic brain injury.